1H-Pyrrole-2,5-dione, 3-[(3α,5α,13α,14β,17α)-3-hydroxy-4,4,14-trimethylandrost-7-en-17-yl]- - Names and Identifiers
1H-Pyrrole-2,5-dione, 3-[(3α,5α,13α,14β,17α)-3-hydroxy-4,4,14-trimethylandrost-7-en-17-yl]- - Physico-chemical Properties
Molecular Formula | C26H37NO3
|
Molar Mass | 411.59 |
Appearance | Powder |
Storage Condition | 2-8℃ |
1H-Pyrrole-2,5-dione, 3-[(3α,5α,13α,14β,17α)-3-hydroxy-4,4,14-trimethylandrost-7-en-17-yl]- - Introduction
Dysolenticin J is a natural product that belongs to the class of sesquiterpenes. It is produced by some species in the ergot-myceae such as Dyscritothecium cupressi and Pseudopezicula tracheiphila.
Dysolenticin J is a white crystalline solid, soluble in organic solvents such as ethanol and dichloromethane. It has antifungal activity and inhibits the growth of some pathogenic fungi. In addition, it also shows the activity of inhibiting breast cancer cells.
Regarding the preparation method, Dysolenticin J can be extracted and isolated from the producing strain. A general preparation method comprises extracting the fermentation product with an organic solvent such as methanol, followed by isolation and purification steps such as column chromatography.
Regarding safety information, toxicological and biological studies on Dysolenticin J are still relatively limited, so its safety and side effects are still unclear. During use, laboratory safety procedures should be followed and appropriate personal protective measures should be taken. At the same time, Dysolenticin J should be stored in a cool and dry place, away from fire sources and combustibles.
Last Update:2024-04-09 21:49:45